- In most advanced countries, the cost of cancer absorbs a growing portion ofresources owing to the changes in risk factors, the availability of more advanced diagnostic procedures and specific treatments, and population ageing. In Italy, 2% of the population have been diagnosed with cancer and this percentage is set to rise. In order to plan interventions, it is important to be able to measure and project the impact both in terms of people and public expense.The EPICOST project, funded by the Ministry of Health (CCM 2014 programme), aims at: 1. describing the patterns of care and the economic resources allocated to cancer patients in some areas covered by population-based cancer registries; 2. forecasting the amount of patients and relative costs, according to different scenarios; 3. assessing the changes at regional level in health spending induced by specific preventive measures (for example, screening programmes), therapeutic measures (for example, use of expensive new biological drugs) and demographic dynamics.
The clinical and demographic information on cancer patients provided by eight population-based cancer registriess are linked individually with economic information from administrative sources (on hospital admissions, outpatient/ambulatory services, drug prescriptions).The distribution of patients and the associated economic expenditures is estimated for the whole pattern of care, divided into three clinically relevant phases: initial phase (one year after diagnosis), continuing phase (between the initial and final phases), final phase (one year before death) and specific cost profiles are built for all the variables that can influence the pattern of care.
Dynamic micro-simulation models are used to project cost estimates in both geographical and temporal terms.
A software is developed for the data management ; to identify diagnosis and treatment profiles; to estimate the number of prevalent cases and cost profiles for each phase of the disease.
- Silvia Francisci, Andrea Piano Mortari
- Francisci, Guzzinati, Mezzetti, Crocetti, Giusti, Miccinesi, Paci, Angiolini, Gigli (2013). Cost profiles of colorectal cancer patients in Italy based on individual patterns of care. BMC Cancer, 13: 329. https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-13-329
- Gigli, Warren, Yabroff, Francisci, Stedman, Guzzinati, Giusti, Miccinesi, Crocetti, Angiolini, Mariotto (2013). Initial Treatment for Newly Diagnosed Elderly Colorectal Cancer Patients: Patterns of Care in Italy and the United States. J Natl Cancer Inst Monogr 2013. https://academic.oup.com/jncimono/article/2013/46/88/966235/Initial-Treatment-for-Newly-Diagnosed-Elderly