{"id":32940,"date":"2021-11-23T07:43:03","date_gmt":"2021-11-23T07:43:03","guid":{"rendered":"https:\/\/www.irpps.cnr.it\/coi-sensitivity-analysis-for-maculopathies\/"},"modified":"2026-03-02T13:01:56","modified_gmt":"2026-03-02T13:01:56","slug":"coi-sensitivity-analysis-for-maculopathies","status":"publish","type":"page","link":"https:\/\/www.irpps.cnr.it\/en\/coi-sensitivity-analysis-for-maculopathies\/","title":{"rendered":"COI Sensitivity Analysis for Maculopathies"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"32940\" class=\"elementor elementor-32940 elementor-2675\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-78ebfca5 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"78ebfca5\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3f272ea4\" data-id=\"3f272ea4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7055f55e elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"7055f55e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-162a3224\" data-id=\"162a3224\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1a9f7d5f elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"1a9f7d5f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">COI Sensitivity Analysis for Maculopathies<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4691309e elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"4691309e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a37bba8\" data-id=\"a37bba8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3d325e56 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"3d325e56\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-34af4b8e\" data-id=\"34af4b8e\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1e16d578 elementor-widget elementor-widget-text-editor\" data-id=\"1e16d578\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"vc_row vc_row-fluid\"><div class=\"content vc_column_counter_2\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column wpb_content_element \"><div class=\"wpb_wrapper\"><p>The research work, conducted in collaboration with the Economic Evaluation and HTA center of CEIS, Faculty of Economics at the University of Rome Tor Vergata, involves the development of a probabilistic sensitivity analysis related to the Cost of Illness estimates for maculopathies in Italy. Within economic evaluations, one of the most critical aspects is the uncertainty of the parameters used in the model, which can compromise the reliability of the estimates obtained. To this end, various methodologies have been developed in the literature to estimate the uncertainty of economic models (One\/multi-way deterministic sensitivity analysis, bootstrap simulation, Probabilistic sensitivity analysis, etc.). However, in the context of economic evaluations and Cost of Illness models in particular, probabilistic sensitivity analysis with Monte Carlo simulations represents one of the most recommended methods, and the estimation of 95% confidence intervals is one of the most understandable indicators for communicating the uncertainty of economic results to Health System stakeholders.   <\/p><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row vc_row-fluid\"><div class=\"sidebar sidebar-builder widget-area vc_column_counter_1\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column wpb_content_element \"><div class=\"wpb_wrapper\"><p><strong>Abstract:<\/strong><\/p><\/div><\/div><\/div><\/div><div class=\"content vc_column_counter_2\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column wpb_content_element \"><div class=\"wpb_wrapper\"><p>The objective of the analysis is to estimate the uncertainty of the parameters used in a previously developed Cost of Illness model for maculopathies in Italy. Specifically, the project aims to develop an Excel-based model capable of estimating the 95% intervals of the main results obtained from the CoI model through Monte Carlo simulations, associating specific probability distributions with each parameter used within the model. <\/p><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row vc_row-fluid\"><div class=\"sidebar sidebar-builder widget-area vc_column_counter_1\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column wpb_content_element \"><div class=\"wpb_wrapper\"><p><strong>Participants:<\/strong><\/p><\/div><\/div><\/div><\/div><div class=\"content vc_column_counter_2\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column wpb_content_element \"><div class=\"wpb_wrapper\"><p>Andrea Marcellusi, Fabio Palazzo, in collaboration with EEHTA-CEIS. Faculty of Economics, University of Rome \u201cTor Vergata\u201d. <\/p><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-50e67f23\" data-id=\"50e67f23\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-177fec00 elementor-widget elementor-widget-heading\" data-id=\"177fec00\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Participants<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d65506f elementor-align-left elementor-widget elementor-widget-button\" data-id=\"d65506f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/ceistorvergata.it\/ceis-researchers\/70-1379\/marcellusi\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Andrea Marcellusi - <b>project lead<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5972861a elementor-align-left elementor-widget elementor-widget-button\" data-id=\"5972861a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.irpps.cnr.it\/en\/fabio-palazzo\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Fabio Palazzo<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7daff465 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"7daff465\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.irpps.cnr.it\/en\/sita-social-informatics-and-technology-assessment\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\"><b>Other SITA projects<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>COI Sensitivity Analysis for Maculopathies The research work, conducted in collaboration with the Economic Evaluation and HTA center of CEIS, Faculty of Economics at the University of Rome Tor Vergata, involves the development of a probabilistic sensitivity analysis related to the Cost of Illness estimates for maculopathies in Italy. Within economic evaluations, one of the [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-32940","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/pages\/32940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/comments?post=32940"}],"version-history":[{"count":1,"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/pages\/32940\/revisions"}],"predecessor-version":[{"id":32944,"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/pages\/32940\/revisions\/32944"}],"wp:attachment":[{"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/media?parent=32940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/categories?post=32940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.irpps.cnr.it\/en\/wp-json\/wp\/v2\/tags?post=32940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}