Patients recovered from childhood tumors represent an emblematic group and particularly suitable for the study of clinical follow-up and psycho-physical, social and work rehabilitation paths: the quality of the diagnosis is generally very good and well documented, the treatment is for mostly done in specialized structures and on the basis of carefully tested and continuously updated protocols; this makes it easier to study the pathways following the treatment phase. However, due to the length of the observation period required, there are only scattered data globally on the prevalence in the general population of adult childhood cancer survivors of all ages and many pediatric cancer survivors are now adults (long- survivors) who enter the age groups at risk of incidence for chronic degenerative diseases.

The CHILDPREV project, funded by the Ministry of Health (CCM 2012), aims, among others, to provide an overall epidemiological picture of the prevalence, incidence and trends of childhood cancers in order to evaluate their future evolution.

With this in mind, the extent of the prevalent adults of all ages who survived a tumor in pediatric age was estimated, through the use of ad hoc statistical methods. In particular, the Childprev method (Simonetti, Gigli, Capocaccia, Mariotto, 2008) was applied to the data of the Cancer Registries that had at least 15 years of incidence and follow-up data of the state in life, to obtain the estimate of the complete prevalence in adulthood (15+) for all cancers together, and for the most frequent prevalent sites among children who get cancer: Hodgkin's lymphomas, acute lymphatic leukemia and central nervous system tumors

Francisci, Guzzinati, Dal Maso, Priest, Buzzoni, Gigli (2017). Living after cancer diagnosis during childhood: A population-based estimation in Italy. International Journal of Cancer http://onlinelibrary.wiley.com/doi/10.1002/ijc.30665/full